Our Nourishing Hormone – GABA, Sleep, Anxiety, and Its Impact on Cycles & Menopause

Progesterone is often called the “nourishing hormone” plays a critical role in maintaining the body's overall health and well-being. This essential hormone is involved in various physiological processes, including metabolism and growth, contributing to the body's ability to function optimally. Its effects can significantly impact hunger regulation and energy levels, highlighting the importance of this hormone in daily life.” for good reason. Produced primarily in the ovaries after ovulation, progesterone plays a vital role in regulating the menstrual cycle, preparing the body for potential pregnancy, and supporting a healthy mood and nervous system. What many people don’t realize is that progesterone is deeply intertwined with our brain chemistry—especially the neurotransmitter GABA, which promotes calm, relaxation, and sleep.

As progesterone levels rise in the second half of the menstrual cycle, known as the luteal phase, it significantly boosts GABA activity in the brain. This is why many women often feel more calm and centered during this particular phase—especially when their progesterone levels are healthy and well-balanced. However, if progesterone levels are found to be low, or if ovulation does not take place (a common issue experienced in conditions such as PCOS or during the transitional period of perimenopause), this calming effect is unfortunately lost. The result of this imbalance? A range of symptoms can emerge, including heightened anxiety, sleep disturbances, mood swings, and even an increase in PMS symptoms, which can significantly affect overall well-being.

In perimenopause and menopause, when ovulation becomes irregular and eventually stops, progesterone production drops significantly. This shift can leave women feeling more anxious, emotionally sensitive, and prone to insomnia. Addressing this hormonal change is not just about symptom relief—it's about restoring balance to both the body and mind.

At our practice, we take a comprehensive and holistic approach to hormone health, ensuring that all aspects are carefully considered. This approach includes testing progesterone levels at the appropriate time in your menstrual cycle to obtain accurate results. We also utilize bioidentical hormone therapy when it is deemed necessary and beneficial for the individual. In addition, we emphasize the importance of supporting the body’s natural rhythm through a well-balanced diet, effective stress management techniques, and the use of targeted nutraceuticals tailored to your unique needs.

Progesterone is more than just a reproductive hormone—it’s a significant and vital player in your emotional well-being, sleep quality, and overall long-term health. When this hormone is properly optimized, it can help bring a sense of peace, restful sleep, and enhanced resilience to your body at every life stage, contributing to a more balanced and fulfilling life experience.